Advanced AMD Support

  • Protect Your Macular from Degeneration
  • Better Sight in Sunlight
  • Reduce Dry Eyes
  • Relax Your Eyes

Eyestrain Protect

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Study: Lutein & Zeaxanthin In The Eyes

Exp Eye Res. 2000 Sep;71(3):239-45.
Lutein and zeaxanthin in the eyes, serum and diet of human subjects.
Bone RA1, Landrum JT, Dixon Z, Chen Y, Llerena CM.

Abstract

Inverse associations have been reported between the incidence of advanced, neovascular, age-related macular degeneration (AMD) and the combined lutein (L) and zeaxanthin (Z) intake in the diet, and L and Z concentration in the blood serum. We suggest that persons with high levels of L and Z in either the diet or serum would probably have, in addition, relatively high densities of these carotenoids in the macula, the so-called 'macular pigment'. Several lines of evidence point to a potential protective effect by the macular pigment against AMD. In this study we examined the relationship between dietary intake of L and Z using a food frequency questionnaire; concentration of L and Z in the serum, determined by high-performance liquid chromatography, and macular pigment optical density, obtained by flicker photometry. Nineteen subjects participated.

We also analysed the serum and retinas, as autopsy samples, from 23 tissue donors in order to obtain the concentration of L and Z in these tissues. The results reveal positive, though weak, associations between dietary intake of L and Z and serum concentration of L and Z, and between serum concentration of L and Z and macular pigment density. We estimate that approximately half of the variability in the subjects' serum concentration of L and Z can be explained by their dietary intake of L and Z, and about one third of the variability in their macular pigment density can be attributed to their serum concentration of L and Z. These results, together with the reported associations between risk of AMD and dietary and serum L and Z, support the hypothesis that low concentrations of macular pigment may be associated with an increased risk of AMD.

Copyright 2000 Academic Press.

Featured Products

Advanced AMD Support

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Powerful support for your macular to protect from degeneration. Promotes better sight in sunlight.*

Dry Eyes Hydro

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Powerful support for your macular to protect from degeneration. Promotes better sight in sunlight.*

Eyestrain Protect

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Powerful support for your macular to protect from degeneration. Promotes better sight in sunlight.*

Products Based on Science

Check the studies that back our claims, ingredients and formulation. Open and transparent. 

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Study 01 - Lutein & Zeaxanthin

Lutein and zeaxanthin in the eyes, serum and diet of human subjects.

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Study 04: Measurement Of Ocular Blood Flow

Progress in measurement of ocular blood flow and relevance to our understanding of glaucoma and age-related macular degeneration

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Study 02: A One Year Study of the Macular Pigment

A One Year Study of the Macular Pigment: The Effect of 140 Days of a Lutein Supplement.

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Study 05: Macular Carotenoid Supplementation

Macular carotenoid supplementation in
subjects with atypical spatial profiles
of macular pigment.

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Study 03: Placebo-Controlled Study Of Zeaxanthin

Randomized, double-blind, placebo-controlled study of zeaxanthin and visual function...

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Study 06: Supplementation With 3 Macular Carotenoids

Supplementation with all three
macular carotenoids: response,
stability, and safety.

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EyesightLabs™ provides premium nutritional supplements for your eyesight and health. We believe that supplements should benefit your health without negative side-effects. Learn more about the science that supports our formulas.

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